Conclusion : through promoting hfcl proliferation and acting on multiple protein targets , the blood enriching function of ligustrazine can be exerted indirectly 结论:川芎嗪能促进入骨髓成纤维样基质细胞增殖,作用于多个蛋白质靶点,间接发挥补血作用。
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Objective : to investigate the effects of ligustrazine on human bone marrow fibroblastoid stromal cell line ( hfcl ) proliferation as well as the protein expression of hfcl and discuss molecular mechanism of blood enriching functions of ligustrazine 摘要目的:研究川芎嗪对人骨髓成纤维样基质细胞增殖及蛋白质表达的影响,探讨川芎嗪补血作用的分子机制。